Keyword: dgp

Are raised DGP-IgG levels an early sign of celiac disease?

Elevated DGP antibodies (and especially DGP-IgG) are often seen in patients with celiac disease on a gluten-containing diet. They appear to have approximately the same value of the tTG-IgA antibody test. However, it appears that in very young children (i.e., in the first two years of life) DGP-IgG do provide a better test for celiac… Read more »

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In follow-up blood testing, why would tTG be negative and DGP be positive?

If the slightly positive test is the DGP-IgA, you can disregard this value, as it can be misleading. If the DGP-IgG is positive it probably means you’re ingesting small amounts of gluten, possibly from cross-contamination, which are raising antibodies but not enough to trigger a tTG or a mucosal response. Basically, in either case you… Read more »

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