Generally, children at risk for celiac disease are screened at age 3 unless symptoms are seen beforehand. In children younger than 3, with symptoms, antibody testing is usually reliable, especially if it includes DGP-IgG. Children must be eating wheat or barley-based cereals for some time, up to several months, before they can generate an autoimmune… Read more »(Updated .)
Categorized: Celiac Disease Diagnosis
What does the term “potential celiac” mean?
A patient who is a “potential celiac” has positive serology (including the highly specific anti-Endomysium antibodies), possibly has symptoms, and has a negative biopsy. A potential celiac may or may not be put on a gluten-free diet, though we typically lean toward recommending the diet even in those potential celiacs who have no symptoms. Early… Read more »(Updated .)
How do you know that 1/3 of the U.S. population has the genes for celiac disease?
Epidemiologic studies testing large numbers of normal, healthy people from the population at large have established both the prevalence of the HLA-DQ2/DQ8 genes as well as the prevalence of celiac disease (from those with highly positive tTG).(Updated .)
Are certain combinations, or lack thereof, of genes tied to certain symptoms?
Studies have for the most part failed to show a simplistic relation between the type of HLA gene involved (i.e., DQ2 vs. DQ8) and types of symptoms.(Updated .)
My body shouldn’t be producing any antibodies if I only have a non-celiac gluten sensitivity, correct?
Correct. If you have “non-celiac gluten sensitivity”, then by definition antibodies found in celiac patients must not be present.(Updated .)
Are raised DGP-IgG levels an early sign of celiac disease?
Elevated DGP antibodies (and especially DGP-IgG) are often seen in patients with celiac disease on a gluten-containing diet. They appear to have approximately the same value of the tTG-IgA antibody test. However, it appears that in very young children (i.e., in the first two years of life) DGP-IgG do provide a better test for celiac… Read more »(Updated .)
Can an Eating Disorder activate Celiac?
While an eating disorder could theoretically be the traumatic event triggering celiac, it is even more likely that celiac presented itself as an eating disorder, if this is of the anorexia type. Furthermore, there is evidence that celiac can be associated with eating disorders.(Updated .)
Is there any connection between mesenteric lymphadenitis and celiac disease?
Mesenteric lymphadenitis. This condition is not seen more frequently in celiac patients than in the general population. If the condition were to occur as a result of celiac disease, the association should not persist once the gluten-free diet has been established for years. However, sometimes enlargement of lymphoid tissue in the terminal ileum can be… Read more »(Updated .)
If my positive antibody test suggests I may have celiac disease, how do I find out for sure?
If antibody tests and/or symptoms suggest celiac disease, a physician should establish the diagnosis by obtaining tiny pieces of tissue from the small intestine to check for damage to the villi. This is done via endoscopic biopsy. Under sedation, the physician eases a long, thin tube called an endoscope through the mouth and stomach into… Read more »(Updated .)
What are the insurance codes correlated with the HLA/DNA tests for celiac disease?
A genetic test shows if you have the gene associated with the disease but doesn’t diagnose that you have it. Genetics tests are often used to understand whether there are risk factors for relatives of someone with celiac disease, or to indicate celiac disease as a likely cause if other methods of screening have been… Read more »(Updated .)