Keyword: iga deficiency

How common is IgA deficiency in those with celiac disease?

2-5% of those with celiac disease are IgA-deficient, and 0.5-1% of the general population. If IgA deficient, or if there is some other equivocating factor to potentially compromise the blood test, then an EMA blood test is also given.

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What can I do about IgA deficiency?

You can’t do anything about IgA deficiency. However, it also doesn’t lead to any clinical issues. If you are attempting to get an accurate diagnosis for celiac disease and you know you’re IgA deficient, or if there is some other equivocating factor to potentially compromise the blood test, then an EMA blood test should also… Read more »

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Is it possible to have a negative blood test, but a positive biopsy?

While rare, it is possible to have a negative blood test and still have celiac disease. tTG sensitivity is approximately 98%, which means that 2% of all celiacs may have a normal tTG level. Sometimes tTG antibodies are not produced enough to show up in the blood stream and can only be detected in the… Read more »

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