Keyword: genes

Can you have celiac disease without having the genes for it?

This topic raises much debate. The current thought shared by the many physicians and scientists is that 1-2% of celiacs may not possess the celiac-specific genes HLA-DQ2 and/or DQ8. Our Dr. Guandalini and Dr. Bob Anderson, chief scientific officer of ImmusanT, believe the genes are necessary to initiate the immunologic response of celiac disease, hence… Read more »

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Do most people with celiac disease have the gene turned on at birth?

For celiac disease to develop, you don’t just need the gene(s), but also the contribution of several environmental factors (the first one being gluten, of course), hence the fact that celiac disease can appear at any time and at any age for those who have the gene(s).

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Are having the genes and symptoms enough to diagnose celiac disease?

No. Many people have the genes and the symptoms, but do not have the disease. It’s difficult to diagnose because the symptoms are common to many health disorders. In addition, nearly 1/3 of the population has at least one of the genes and many never develop the disease.

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