Keyword: environment

If three things come together to cause celiac disease—over-responsive immune system, genetic predisposition and individual environment—what is meant by individual environment?

“Individual environment” means the combination of factors that combine to create the ideal conditions for celiac disease to develop: modalities of delivery (C-section vs. natural birth), type of bacteria that inhabits one’s gut, early and excessive use of antibiotics, episodes of infections suffered, traumas and possibly other factors yet to be identified.

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Do most people with celiac disease have the gene turned on at birth?

For celiac disease to develop, you don’t just need the gene(s), but also the contribution of several environmental factors (the first one being gluten, of course), hence the fact that celiac disease can appear at any time and at any age for those who have the gene(s).

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