Celiac
Answer Bank

Frequently Asked Questions

Q

If I understand correctly, there isn’t a gluten allergy because celiac is an autoimmune response, while gluten intolerance is a gastrointestinal response. For someone to have a gluten allergy they would have to be allergic to the proteins of glutenin and gliadin and have an allergic response. Is it even possible to have a true allergy to glutenin and gliadin? Obviously I am not an expert but from my research there isn’t a gluten allergy, it is a misused/inaccurate phrase that is used to describe gluten intolerance and non celiac gluten sensitivity.

When we say “wheat allergy” it is clear that there is an allergic response to the ingestion of wheat; and because it is only protein that causes an allergic reaction, one can assume “wheat allergy” is indeed a reaction to the protein content of wheat, hence most likely either glutenins or gliadins (although wheta also contains minuscule amounts of other proteins). As for what we call “non celiac-gluten sensitivity”, there is evidence that gluten is the real culprit in only a small fraction of patients who report this condition. Other causes have been found in these subjects, and none in some. The term is therefore an umbrella term that should be rephrased as “Non-Celiac Wheat Intolerance Syndrome”. May, 2017
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