Celiac
Answer Bank

Frequently Asked Questions

Q

Does the villous atrophy present differently at the lab or look the same? In other words, with persistent villous atrophy after a gluten free diet, would the biopsy confirm active celiac disease and/or another cause?

It depends on what the pathologist describes. Villous atrophy is important and well defined, but if in addition the pathologist for instance describes intense neutrophilic infiltration, this would point toward something like Crohn’s, or with eosinophils, this could be eosinophilic enteritis, and so on. In a few words: villous atrophy is only part of the story and has to be read in context. July, 2015

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