Answer Bank

Frequently Asked Questions


Can celiac disease cause watery blisters on the skin?

Blisters on the skin (part of the dermatitis herpetiformis version of celiac disease) are an inflammatory result due to a deposition of anti-tTG antibodies in the skin. In fact, recent studies have demonstrated that IgA antibodies against epidermal transglutaminase 3 play an important role in the pathogenesis of dermatitis herpetiformis. See Nakajima K. Recent advances in dermatitis herpetiformis. Clin Dev Immunol. 2012;2012:914162. doi: 10.1155/2012/914162. Epub 2012 Jul 2: http://www.ncbi.nlm.nih.gov/pubmed/22811741 June, 2013