Answer Bank

Frequently Asked Questions


Can Accutane trigger celiac disease?

Although there is no clinical data yet to prove that Accutane (or any forms of retinoic acid), which treats severe acne, can trigger celiac disease, it is true that retinoic acid in animal systems–in the context of a mipre-existing even minimal intestinal inflammation–may amplify an inflammatory response. If we put this in context of celiac disease, then the implication could be that retinoic acid triggers celiac. Even in the absence of a clear clinical evidence, we suggest caution with the use of Accutane in subjects who have the gene(s) for celiac disease. May, 2017