Categorized: Non-Celiac Gluten Sensitivity

If I understand correctly, there isn’t a gluten allergy because celiac is an autoimmune response, while gluten intolerance is a gastrointestinal response. For someone to have a gluten allergy they would have to be allergic to the proteins of glutenin and gliadin and have an allergic response. Is it even possible to have a true allergy to glutenin and gliadin? Obviously I am not an expert but from my research there isn’t a gluten allergy, it is a misused/inaccurate phrase that is used to describe gluten intolerance and non celiac gluten sensitivity.

When we say “wheat allergy” it is clear that there is an allergic response to the ingestion of wheat; and because it is only protein that causes an allergic reaction, one can assume “wheat allergy” is indeed a reaction to the protein content of wheat, hence either glutenins or gliadins (or both). As for what… Read more »

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How do you know non-celiac gluten sensitivity exists?

We don’t. Some studies have shown that some people who do not have celiac disease do get sick when eating gluten and get better when not eating it. It’s important to keep in mind, however, that when one removes gluten one also removes large amounts of FODMAP (Fructose, Olygosaccharides, Disaccharides, Monosaccharides And Polyols)-containing foods that… Read more »

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Why don’t you recognize tests (stool tests or otherwise) for non-celiac gluten sensitivity that are currently available through companies like Enterolab or Cyrex?

We only embrace tests that have endured rigorous scientific evaluations. So far, these tests have received no evidence-based support. Enterolab has never successfully published anything on the accuracy of stool tests (nor have any other stool test manufacturers, to our knowledge) making it difficult to confirm the research results. Because of this, we must make… Read more »

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Some have suggested the term “gluten-related disorders” instead of “gluten intolerance” as an umbrella term for celiac disease, gluten sensitivity and wheat allergy. What are your thoughts?

Many publications have appeared discussing different definitions; a universal standard is still a work in progress. Until an official agreement is reached, we believe our umbrella term, “gluten intolerance,” is a valid one, as it carries no implications of a specific mechanism for the adverse effects of gluten ingestion. That said, we also agree with… Read more »

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What is non-celiac gluten sensitivity?

Non-celiac gluten sensitivity is an adverse food-induced reaction, possibly immune-mediated, but for which we have no diagnostic test available. This is a reaction in the digestive tract that causes gastrointestinal symptoms similar to irritable bowel syndrome (IBS). It may also lead to other body systems problems, such as fatigue, headache, etc. Unlike celiac disease however,… Read more »

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