Categorized: Celiac Disease Diagnosis

I had the Antibody Array 3 Wheat/Gluten Proteome Sensitivity & Autoimmunity blood test. Is this the right test to diagnose celiac disease?

No, you should have both the tTG-IgA and total serum IgA tests to screen for celiac disease. As long as you produce IgA (total serum IgA confirms you do), tTG-IgA is 98% accurate in measuring elevated antibodies. If you’re IgA deficient, or if there is some other equivocating factor to potentially compromise the blood test,… Read more »

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What is an EMA blood test?

The anti-endomysial antibody test (EMAIgA), EMA-IgA, is very specific for celiac disease. It’s estimated that a person with an elevated titer of EMA is almost assured of having celiac disease. However, the EMA test isn’t as sensitive as the tTG-IgA test; about 5-10% of celiacs do not have a positive EMA test.

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Can you have celiac disease without having the genes for it?

This topic raises much debate. The current thought shared by the many physicians and scientists is that 1-2% of celiacs may not possess the celiac-specific genes HLA-DQ2 and/or DQ8. Our Dr. Guandalini and Dr. Bob Anderson, chief scientific officer of ImmusanT, believe the genes are necessary to initiate the immunologic response of celiac disease, hence… Read more »

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