Categorized: Celiac Disease Diagnosis

Is there any connection between mesenteric lymphadenitis and celiac disease?

Mesenteric lymphadenitis. This condition is not seen more frequently in celiac patients than in the general population. If the condition were to occur as a result of celiac disease, the association should not persist once the gluten-free diet has been established for years. However, sometimes enlargement of lymphoid tissue in the terminal ileum can be… Read more »

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How do you know that 1/3 of the U.S. population has the genes for celiac disease?

Epidemiologic studies testing large numbers of normal, healthy people from the population at large have established both the prevalence of the HLA-DQ2/DQ8 genes as well as the prevalence of celiac disease (from those with highly positive tTG). Once one knows that the disease is found in 1/100 of the general population, then one can calculate… Read more »

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Are raised DGP-IgG levels an early sign of celiac disease?

Elevated DGP antibodies are often seen in patients with celiac disease on a gluten-containing diet. They appear to have exactly the same value of the more established tTG-IgA antibody test, and offer no advantage over tTG. However, it appears that in very young children (i.e., in the first two years of life) DGP do provide… Read more »

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At what age should children get tested for celiac disease?

Generally, children at risk for celiac disease are screened at age 2 or 3 unless symptoms are seen beforehand. In children younger than 3, with symptoms, antibody testing may not always be accurate. Children must be eating wheat or barley-based cereals for some time, up to one year, before they can generate an autoimmune response… Read more »

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My blood tests came back negative, but I’d only been eating gluten for about a month. I also had an endoscopic biopsy after three months of eating gluten where they found patchy infiltration with lymphocytes. My doctor doesn’t want to diagnose me with celiac disease because the blood tests were negative. Should I seek a second opinion?

If you had been gluten-free for a long time and only ate gluten for one month prior to your blood work then it may not have been accurate. In other words, you probably have celiac disease. Consider having another endoscopic biopsy after one year on a strict gluten-free diet to see if complete healing of… Read more »

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